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Our work underscores the value of exploring water-mediated interactions to study ligand binding, and highlights the difficulty of optimizing polar interactions due to high desolvation penalties.
Our work underscores the need for an integrative approach that recognises multiple facets of parasitism, such as their extended phenotypes.
Our work underscores the need for additional data on the persistence time of transmitted and acquired resistance and the probability of transmission with and without PrEP.
Our work underscores the fact that human nevi are capable of occasional, induced proliferation and transformation.
In general, our work underscores the importance of testing new genetic anticancer agents and treatment regimens on primary cancer specimens.
Our work underscores the complexity of this disease and the exigency to explore previously overlooked mechanisms of treatment resistance and evasion of apoptosis.
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Our work also underscores the potential of the mobilome for orchestrating Rickettsia host adaptations.
However, our work also underscores the importance of maintaining a firm linkage between centrosomes and nuclei during interphase, to insure that only one centrosome is available per nucleus for division.
Such deliberate manipulation of the gut microflora is a long way off — years and years off, according to Gordon — but its possibility "is what this first phase of our work is underscoring, and we hope it will turn out to be an important tool in the fight against obesity".
In fact, this latter experimental work underscores an advantage of our in vitro coculture system: in studying cancer evolution using this cell line panel, pathways can be manipulated and direct causal effects can be examined.
That work underscores the growing presence of universities and colleges as advertisers in the media.
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