Exact(1)
Nevertheless, the error level due to C→T transitions (3%) is a serious concern in hDNA analyses since, unlike in our study, discovery and correction of these artefacts may prove difficult.
Similar(59)
In our study, the discovery that two B3 isolates could have emerged as a result of a previous recombination event raises the possibility that recombination events among enteroviruses associated with HFMD occur more frequently in nature.
These range from a candidate gene approach [ 24], selection of genes using a biological approach [ 23] and similar to our study, a discovery-based approach using supervised analyses correlated with clinical outcome [ 13].
According to a recent study, discovery and development costs, a key indicator for the industry, tripled from 1999 to 2006, to nearly $15 a barrel.
A practical utility of our study is the discovery of drug targets that can be further developed for therapeutic intervention in PEL (Fig. 7).
The discrepancy between our study and the discovery study can have several reasons.
A further important finding of our study was the discovery of regulated genes coding for cell adhesion.
An intriguing result from our study is the discovery that 11% of mature Math5 transcripts in the adult cerebellum are bona fide spliced mRNAs.
Our study describes the discovery of GRP78va, a novel cytosolic isoform of GRP78/BiP, and the first characterization of the modulation of UPR signaling via alternative splicing of nuclear pre-mRNA.
Together, our study describes the discovery of the first drug-like activators of IDE, the characterization of which provides several new insights into the mechanistic basis for pharmacological activation of IDE.
The aim of our study was the discovery of new helpful immunohistochemical markers for the detection and definition of FTC.
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