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Note the small SiO2 range of our samples, indicating low fractionation of the primitive magma.
Intrasubtype diversity was already high among our samples, indicating that the HIV epidemic in Kinshasa was already mature by the mid-1980s.
The phosphorylated form of estrogen receptor α was undetectable in our samples, indicating that this receptor was inactive, whereas estrogen receptor α phosphorylation was evident in MCF-7 cells (used as a positive control).
miRCat was able to predict 123 mature miRNA sequences corresponding to 87% of the known miRNAs identified in our samples, indicating that the prediction algorithms implemented in miRCat are highly efficient in identifying plant miRNAs.
Also, little is known about Ag and U concentrations in breast milk, which varied largely in our samples, indicating some influence of maternal exposure to these elements, however the concentrations were low.
In addition, interestingly, recombination between TRDV1 and various J exons in TCRA was observed in our samples, indicating that this exon, although defined as a V exon of the TCR delta gene, may also function as a V exon of TCRA (Supplementary Figure 2).
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The absence of rhamnose in our samples indicates the absence of tree gums, at least gum arabic [50], whereas the presence of fucose strongly suggests the presence of tragacanth-type gums [51].
LD block and tagging analysis (r2≥0.9) of the three PRKG1 top SNPs in our samples indicated that they map in different haplotype blocks (Figure S3).
Furthermore, an overexpression of ALDH1, detected in a substantial number of our samples, indicates that CTCs might often display tumor stem cell characteristics, highlighting their role in metastasis formation.
However, the apparent heterogeneity of EMT-associated proteins in our samples indicates that these molecules may have redundant functions, fine-tune downstream pathways and/or serve specific purposes in a temporal and spatially regulated fashion.
The results of semiquantitative real-time RT-PCR on our samples indicate that hepsin is significantly overexpressed in 14 out of 14 cases, IQGAP2 in 8 of 14, and HER3 in 10 of 14 cases.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com