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Also, our present models do not clearly display changes in cortical thickness that may represent an important pathology of Alzheimer's disease [15].
To make it clear why we desperately need a richer, more nuanced account of medical reasoning, Wright gives a brilliant analysis of the complex internal structure of our concepts of health and disease, showing that our present models are wholly incapable of dealing with the realities of actual human disease.
Everyone knows that our present models are underperforming.
As shown in our present models, Arg58 and His84 are positioned in the vicinity of the SRL.
We cannot confirm this quantitatively with our present models, which are built to simulate flat-field rather than punctate stimuli.
As suppression of STAT3 had no impact on MCL-1 expression, though in FLT3-ITD_627E cells presumably showing a different signaling, this mode of action might not apply to our present models.
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The discrepancy between the value of 0.3 and our previous estimate of 0.45 arises, because in our present model, contrary to the previous simplified version of the model22, newly recruited vesicles between stimulations can release before the next stimulation.
Analytical results are compared with those obtained from the 2D MEDICI device simulator to validate our present model.
The simplicity of our present model limited the simulation to a sketch.
Our present modeling relies on the differing interference characteristics along the x-axis for the perpendicular and parallel polarizations.
Thus, no route completion constraint is considered in our present model because it might overextend routes into distant suburbs with insufficient demand density.
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