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However, differences in transcript abundance in our normalized libraries may reflect different normalization efficiency rather than genuine differences in gene expression.
For the libraries to contain as many expressed full-length clones as possible, we consider our normalized library a good compromise between large clone size and efficient normalization.
Our normalized empirical comparisons show that our heuristics handily outperform the existing state space heuristics.
They review them, have access to them at any point in time, get the information on those positions on a regular and recurring basis as part of our normalized reporting.
Finally, we demonstrate the power of our normalized smart-building metadata schema paradigm by using the standardized sensor and relationship representations to implement both simple (e.g. finding errant zones, identifying inefficient air handling subsystems to save energy) and sophisticated applications (e.g finding rough occupancy estimates) that scale across real-world smart-buildings.
Roger A. Pielke, Jr., of the University of Colorado, who has spent years analyzing hurricane damage patterns, noted that a tool he helped create to anticipate hurricane damage projects a substantial risk of big losses from Hurricane Irene: With ICAT (an insurance company) I helped to build this online damage estimator based on our normalized loss database.
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For demonstration, we created a toy signaling network using our normalized-Hill differential equation approach.
We performed sensitivity analysis on our normalized-Hill β-adrenergic model using the same approach as that implemented for our toy network.
We next applied our normalized-Hill modeling approach to the cardiac β-adrenergic signaling network, the major pathway that regulates contractility, metabolism, and gene regulation of the heart [ 20].
To enhance the size of our dataset, the 12,319 unique sequences generated from our six normalized libraries were secondarily assembled with these GenBank sequences using the CAP3 component of the ESTPiper.
I FIRST visited China in 1979, a few months after our countries normalized relations.
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