As illustrated in Fig. 2, our methodology comprises three steps: (i) obtaining the confounding adjusted signal score for each drug ADR pair from individual health data; (ii) calibrating the signal scores based on the empirical distribution derived from a set of reference negative controls; (iii) combining calibrated signal scores from disparate databases.
A "plug and play" methodology comprising a generic linking apparatus may enable rapid design and optimization.
A hybrid methodology comprising the Plackett Burman (PB) design method, artificial neural networks (ANN) and genetic algorithms (GA) was utilized.
This paper proposes an iterative methodology comprising mechanisms for guiding sample size selection and self-assessing result accuracy.
In this work we suggest a methodology comprising the design and use of cost-effective, sustainable, and environmentally friendly process for biofuel production compatible with the market demands.
The methodology, comprising length-scale dependent constitutive model and scale-consistent fatigue indicator parameters, is calibrated and validated for representative (measured) dual-phase microstructures under strain-controlled low cycle fatigue conditions.
The current methodology comprising a blend of first-principle calculations and KLMC model provides a very powerful fundamental tool for predicting the optimal dopant concentration in ceria related materials.
Furthermore, an analytical methodology comprising a sample preparation step based on solid phase extraction has been implemented using this "tailor made" imprinting system as sorbent, for the selective isolation/pre-concentration of deltamethrin from olive oil samples.
The Geoviticulture Multicriteria Climatic Classification (MCC) System is engaged with a methodology comprising three viticultural climatic indexes of different natures: hydric type (dryness index), heliothermal type (Huglin index), and Nictothermal type (Cold Night Index).
There have been many large national and international efforts that have led to a well-established validation methodology comprising analytical, inter-program comparison and empirical validation elements, and a significant number of tests have been developed.
