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Herein, we have developed our initial hypothetical algorithm for use of TH in the treatment of traumatic HS based on existing data and the theoretical discussion above.
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Our review provides novel insights into the field and proposes a new initial hypothetical algorithm for use of TH in trauma and HS in the future.
The initial hypothetical model suggested chronic inflammation as the cause of pulmonary fibrosis, whereas a subsequent hypothesis posited epithelial injury and impaired wound repair as the etiology of fibrosis without preceding inflammation.
The development stage for a PRO questionnaire, as proposed by Fayers and Machin [ 2], include generating an initial hypothetical model, defining the target population, generating items by qualitative methods, followed by pre-testing and field-testing the questionnaire.
The data from steps B and C will be analysed and interpreted together in step D to understand the relationships between the elements of the initial hypothetical causal chain.
Our initial, instinctive reaction to this rather outlandish hypothetical is to want to hold the negligent defendant liable.
Our initial confusion soon turned into ecstasy.
See our initial proposal.
Our initial problem?
Our initial online interchanges went well.
"Our initial attack time is pretty good".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com