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Our elucidation of the processes that underpin human growth is central to understanding normal as well as abnormal development.
Thus, based on our elucidation of the CAPN3 cleavage motif we find explainable disturbances in the levels of two predicted substrates in patients.
Our elucidation of the molecular defect caused by mutations in Rab7 illustrates an alternative mechanism: toxic misregulation of native function.
As SIRT4-repressed glutaminolysis inhibited cancer cell growth, our elucidation that SIRT4 acts as a target gene of CtBP further strongly supports the view that CtBP can be a potential target of tumor therapeutic strategy.
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The interpretation of these differences of association is complex: our first elucidation would be that although we were unable to detect early recovery of organ failure, being able to recruit the microcirculation might have impact on survival.
Beyond the optimal Dfs value that produces the minimum-EER performance, this is where our prior elucidation holds: the more the less-discriminative dimensions are being utilized, the worse the discretization performance would be.
Following our recent elucidation of the fact that bioactive 5-deazaflavins stabilize and activate p53 by binding directly to the HDM2 RING domain, here we have presented a comprehensive SAR analysis of 5-deazaflavin as inhibitors of p53 ubiquitination by the p53-specific ubiquitin E3 ligase HDM2.
Our recent elucidation of a community map for PKA shows clearly how the C-tail and β strands one and two function as an integrated community in the closed conformation, whereas this community is uncoupled in the apo conformation (McClendon, C. et al., manuscript in preparation).
Lehman Brothers collapses, the stock market tumbles, capitalism quakes – can we turn to our bookshelves for elucidation?
Public health implications of our findings await elucidation of the contexts in which and mechanisms through which maternal depression may affect growth in children.
Although the details of this biological event require further elucidation, our studies provide additional evidence to support this hypothesis.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com