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In summary, our current study identifies the NFAT molecular pathway as an important regulator of TRAIL.
Our current study identifies a novel mechanism, whereby HIF-1α counteracts both chemotherapy-induced senescence and apoptosis: We present conclusive evidence for the capacity of HIF-1α to suppress the induction of the tumor suppressor p53 in response to 5-FU under normoxic conditions.
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Our current study identified miR-185 as a regulator in the sensitivity of gastric cancer cells to chemotherapy.
Our current study identified a further three 450 genes that were co-up-regulated in response to permethrin exposure in ALHF house flies.
Our current study identified a novel peptide (SWQIGGN) that can 1) specifically bind to ovarian cancer cells and 2) control ovarian cancer in vitro and in vivo.
Our current study identified GRHL2 as a novel transcriptional regulator for numerous EDC genes, many of which are directly involved in the skin barrier formation.
Our current study identified the conversion of naïve/effector T cells into senescent T cells as a novel mechanism utilized by human tumor cells to induce immune tolerance.
Our current study identified almost 25% of premenopausal patients with a genetic background associated with clearly significant poor outcome and hypothetically associated with altered treatment outcomes.
Our current study identified four AP2 genes containing unambiguous targeted sites for binding Rc- miR172, which could provide a potential clue to dissect the mechanisms underlying the AP2 gene regulation in castor bean.
Our current study identified U6 snRNA to be the putative Tip110-binding target through the yeast three hybrid cloning and further confirmed the binding specificity through the gel shift mobility assay.
Our current study identified aggressiveness, male sexual activity, and deceptive mating behavior in presence of an audience as consistent, species-specific behavioral traits, while decreased preference expression due to an audience ('audience effects' sensu ) was found to be a universal feature in all but one of the investigated species.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com