Which brings us to our central issue: what should she have done at the time?
In our view, the central issues concern the nosological status and the diagnostic boundaries of schizophrenia and schizotypal conditions, along with the consequences of understanding how important self-disorders are in understanding these phenomena.
Some central issues our study will examine include to what extent the AUSFTA requires, facilitates, or is likely to result in, changes to Australia's generic pharmaceutical industry, as well as its PBS cost-effectiveness system of pharmaceutical regulation.
These should be among the central issues of our age.
His work engages with the central issues of our age and will inevitably cause controversy.
Now most conservatives seem incapable of even acknowledging the central issues of our moment: wage stagnation, inequality, health care, global warming.
We honor the chain of command, so we trust him with the most central issues of our time -- war, peace, the nuclear button.
Its director, Aaron Betsky, whose day job is running the Cincinnati Art Museum, has banned buildings or models of them from the exhibition, the better to "point the way towards an architecture liberated from buildings to engage the central issues of our society".
But I want to emphasize, I believe life is one of the central issues of our day, and I believe that every human life at every phase is unique, is beautiful, is a child of a loving God period.
Terrence Des Pres, writing in The Nation, said of him: "In exile from a world which no longer exists, a witness to the Nazi devastation of Poland and the Soviet takeover of Eastern Europe, Milosz deals in his poetry with the central issues of our time: the impact of history upon moral being, the search for ways to survive spiritual ruin in a ruined world".
He notes that we devote far too little attention to these central issues of our day.
