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Due to the integrative approach, our analysis associates several GO terms related to GPI anchors proteins (GO 0006506 GPI anchor biosynthetic process, GO 0016255 attachment of GPI anchor to protein, GO 0006661 phosphatidylinositol biosynthetic process, GO 0046488 phosphatidylinositol metabolic process) with the merozoite stage, prevailing over this shortcoming.

Our results show that this process is related to the schizont stage, as our analysis associates GO 0020033 antigenic variation, GO 0006955 immune response, GO 0050776 regulation of immune response, GO 0002377 immunoglobulin production, GO 0006950 response to stress and GO 0009607 response to biotic stimulus with this stage.

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To this end, there is a risk of residual confounding in our analysis associated with the timing of the measurement of acute severity of illness.

Our functional analysis associated Rgs4 with cell proliferation, cell migration, integrin and endocytosis signaling.

In support of this hypothesis, our pathway analysis associated both upregulation of the myc oncogene and alterations in mitochondrial oxidative phosphorylation with poor outcome.

In our analysis, factors associated with carotid IMT were predominantly traditional atherosclerotic risk factors, whereas eGFR was not independently associated with carotid IMT, which indicated that increased IMT in our patients might be caused at least by traditional risk factors.

Furthermore, in our analysis, cofactors associated with frailty, i.e. sort and number of comorbidities, age, cognitive function, use of a walking device and ADL and IADL function, did not act as confounding factors.

In addition, CCL22 in our analysis was associated with a number of immunomodulatory factors, especially Ip10 and MCP-1.

Other risk factors which were included in our analysis were associated with an increased risk of failed neonatal hearing screening as well.

This may explain the fact that the majority of the factors identified in our analysis were associated with the odds and not the level of oocyst excretion (Table 2).

The goal of the present paper is to continue our study on analysis associated with Greiner-type vector fields introduced in [8].

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