Sentence examples for otherwise essential from inspiring English sources

But they have time to learn and seem to possess little compunction about stomping on the rules — formal and otherwise — essential to a democracy.

Indeed, the virus does not need to acquire (a) mutation(s) that prevent(s) direct binding of the inhibitor to the viral protein, but must rather acquire a mutation that makes it less dependent of a host factor that is otherwise essential for viral replication.

Thus, cell-cycle quiescence can itself maintain stem cells, independent of the signaling pathway otherwise essential for such maintenance.

Furthermore, we found that nonessential genes in otherwise essential complexes frequently exhibit negative genetic interactions with another member of the same complex.

Moreover, N can functionally replace these otherwise essential factors in in vitro translation reactions, and it can further replace the essential helicase activity provided by eIF4A.

We propose that ancient transitions to holocentricity in insects obviated the need to maintain CenH3, which is otherwise essential in most eukaryotes, including other holocentrics.

Thus, attenuation of the DDR at uncapped telomeres can circumvent the need for otherwise-essential telomere capping proteins.

So many people love guns and swear by them -- many of them people with whom I am otherwise in essential political agreement.

The giant, airy interiors conceal a painstakingly executed series of cantilevers designed to avoid your navigating the huge columns that would otherwise be essential for support.

Otherwise, the essential lack of a selfing syndrome in Bulbophyllum clade C supports our principal hypothesis that shifts toward auto-pollination in this group occurred relatively recently.

As expected, reconstruction of the evolution of PriA from HisA with HMM profiles suggest that functional shifts involve mutations in evolutionarily intermediate enzymes of otherwise functionally essential residues or motifs.