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Others rage.
Others rage about it.
Others rage against the long waits and packed tables.
The others rage on, displacing thousands of people, destroying wildlife and ruining vast tracts of once-bucolic mountains.
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Some exiles raged against the sight of foreign troops on the soil of their homeland; others raged against Saddam and prayed for his overthrow, no matter what the cost.
Just as some of us embraced emoticons such as :-( and :-0 while others raged at our inability to express ourselves properly using words and punctuation, so we're embracing emoji, too, from the angry face to the tomato to the hospital to the flexing bicep to the ghost, and indeed the balloon.
Little wonder there is a combination of resignation to one's fate on the one hand and, on the other, rage, frustration and anger.
GG eventually acquired the same shape as all other rage media in that solely existed to exist, an audience for an audience's sake.
HMGB-1 and other RAGE ligands may contribute to damage and host response as part of the danger-associated molecular pattern system [ 14, 15].
We do not know if sRAGE concentrations were enough to bind HMGB-1, after they had scavenged AGEs and other RAGE ligands.
However, in vivo, the importance of other RAGE ligands such as HMGB1, which bind carboxylated glycans, cannot be ruled out since HMGB1 induces IL-6 in macrophages via NF-κB activation, and administration of anti-HMGB1 decreases CAC in Apc/Min+ mice (48).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com