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As in the periphery, NK cells act in concert with T cells and other lymphocytes responsible for CNS pathology and immune regulation.
T-cells can be differentiated from other lymphocytes like B-cells because they contain proteins called T-cell receptors (TCRs) on their cell surface.
The yield of other lymphocytes was also comparable.
No other lymphocytes are generated in this culture system.
CXCR6 is expressed at a high level on NKT cells even under physiological conditions, as compared to other lymphocytes [37].
The proportion of IFNγ-producing γδ-T cells, but not other lymphocytes, was significantly higher when stimulated with live compared with heat-killed bacteria (P<0.0001).
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Here, as for other lymphocyte parameters, no association with nosocomial infections was found.
Their association with B cell follicles prompted early studies on their involvement in B cell activation, and recent work has unveiled an unexpected role in facilitating activation of other lymphocyte subsets, such as invariant natural killer T (iNKT) cells.
Furthermore, the ability to monitor the progress of the infection and the viral pathogenesis is possible through the use of tests that quantify viral load or the peripheral CD4+ T-cells and other lymphocyte sub-type levels.
Other lymphocyte subsets such as CD8+ T cells, natural killer (NK) cells, CD1-restricted T cells and γδ T cells also secrete IFNγ in response to Mtb infection, but they are unable to compensate for the lack of CD4+ T lymphocytes as a source of this cytokine [2].
Already by day 4 after treatment with GK1.5, almost all CD4+ T cells had disappeared and as a consequence, the other lymphocyte sub-populations had proportionately increased.
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