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The 1958BC is largely a white European population (98%); for these analyses 154 individuals of other ethnicity groups were excluded.
However, one needs to be cautious when applying the results of this study to other ethnicity groups, since all women from this study are Chinese.
Results show that, among premutation carriers, Whites tended to have slightly higher CGG repeat size (mean 76, SD ± 24, N = 16) than other ethnicity groups (mean ranging from 62 to 75), although the difference did not reach statistical significance.
Moroccan boys had significantly lower RPQ total and RA and PA scores than all three other ethnicity groups, and boys of mixed ethnicity had significantly lower scores than Dutch and Antillean/Surinamese youths.
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In multivariate analyses, South Asians showed better survival compared to the Other ethnicity group in the individual group comparison, however the overall difference among ethnic groups was not significant (Table 4).
Our results also indicate that, for esophageal cancer, South Asians have better survival compared to the Other ethnicity group.
A significant survival difference only was observed among ethnic groups for patients with non-metastatic disease (p = 0.0498), as shown in Figure 5. Again, South Asians showed better survival compared to the Other ethnicity group (HR = 0.74, 95%CI; 0.56-0.97) in the multivariate analysis.
For the purposes of this analysis we collapsed ethnicity into a seven-category variable (white British, other white, black Caribbean, black African, Asian (Indian subcontinent), mixed ethnicity, other ethnic groups).
The present study was restricted to infants of Dutch ethnicity and cannot be generalized to other ethnic groups, since ethnicity has been shown to be associated with body fat distribution [ 37, 38].
Similarly, it is also difficult to generalise this research to other ethnic groups, as ethnicity was not captured in the online survey and both parent child dyads that were interviewed were Caucasian.
Ninety-one percent of the leukaemia cases were classified as white, based on parental information, the remainder being Asian (3.8%), Black (1%), mixed ethnicity (1.9%), other ethnic groups (0.5%) or unknown.
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