Exact(55)
CloudMade is co-founded by Steve Coast – who actually started OSM in 2004 – and long-time OSM contributor Nick Black.
Our present study revealed that (1) OSM treatment preserved cardiac function and attenuated myocardial apoptosis and fibrosis in a mouse MI model; (2) OSM promoted angiogenesis in the infarct border zone after MI probably via upregulating angiogenic factors VEGF and bFGF; (3) the beneficial effect of OSM in MI mice was abrogated when OSM receptor O β was knocked out.
Further examples include osm-deep-history (www.github.com/osmlab/osm-deep-history), which allows to analyze the history of OSM; Augmented OSM Change Viewer (overpass-api.de/achavi), which allows to analyze a collection of changes submitted to OSM in the form of a 'changeset'; and the tool Who did it?
To localize OSM-induced STAT3 phosphorylation, wild-type rats were treated with OSM in the left eyes and PBS in the right eyes.
A higher affinity anti-OSM antibody is needed to truly examine the role of OSM in RA.
Given that OSM is present in all canine patient tumor samples, it is plausible to infer that OSM in the tumor microenvironment in vivo likely enhances OSA basal Src and STAT3 activation and JAK2 phosphorylation.
Similar(5)
Despite the extensive literature body on the examination of OSM data and OSM mapping efforts as well as on data quality in respect to VGI and OSM in particular, technologies to support these aims have been discussed rarely.
MMP-16 (MT3-MMP) was downregulated by IL-1+OSM in cartilage (10-fold).
Both MMP-1 (10,500-fold) and MMP-13 (3,700-fold 3,700-folddly and highly induced by IL-1+OSM in bovine nasal cartilage.
By day 5 of culture, more than 80% of the proteoglycan was released from the cartilage stimulated with IL-1+OSM in line with previous findings [ 14].
We have previously shown that ADAMTS-1 was only weakly induced in response to IL-1+OSM in a human chondrocyte cell line [ 27] and shows no change in monolayer cultured human articular chondrocytes (JB Catterall, unpublished data).
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