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Every bank is required by OSFI to put aside adequate capital to cover potential losses due to market events.
Risk management exists for two reasons: First, every deposit-taking institution in Canada must have an adequate risk-management system as dictated by the Office of Superintendents of Financial Institutions (OSFI); second, no board member or shareholder of CIBC wants to wake up one morning to find that their firm has blown up.
For compounds where hepatic metabolism plays a significant role, pediatric CLint (per gram of tissue) can be estimated from adult values using the following equation: where OSFI is the isozyme-specific ontogeny scaling factor and CLint,i,adult is the isoenzyme-specific intrinsic CL (per gram of tissue) as denoted in adults.
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CEO of Professional Science Editing for Scientists @ prosciediting.com