Bi-weekly treatments are less effective because fundamental characteristics of romiplostim make oscillations in platelet count unavoidable at this treatment frequency.
All of the patients on E. coli RNA fragments showed an oscillation in platelet counts where the platelet levels declined after the administration of chemotherapy and recovered during the rest phase of the treatment cycle, Figure 1.
Unlike the patients on E. coli fragments, seven patients using yeast RNA fragments failed to demonstrate an oscillation in platelet counts, Figure 2. In these cases platelet levels declined after the administration of chemotherapy but either did not recover or recovered very slowly during the rest phase of the treatment cycle.
For example, Cheyne Stokes respiration, Parkinsonian gait, loss of EEG variability, preterminal cardiac oscillations, neutrophil count in chronic myelogenous leukaemia and fever in Hodgkin's disease all exhibit periodic, more regular variation in the dynamics of disease states [ 142].
Finally, in order to smooth out the oscillations in the number of the counted persons among consecutive frames, we employ a low-pass filter.
In measuring an accurate one-second pendulum, for example, the Italian astronomer Father Giovanni Battista Riccioli persuaded nine fellow Jesuits "to count nearly 87,000 oscillations in a single day".
When the time is longer than the threshold and each stripe appears one by one as they oscillate, the network is counted as a short germ mode (See the temporal oscillations in Fig. S9).
Moreover, there was also a significant delay in initiation of cytoplasmic Ca2+ oscillations in the egg, with the first Ca2+ spike appearing after ∼190 minutes at a luminescence value of 0.34 counts per second.
Neuronal oscillations in cortical networks.
Buzsaki, G. Theta oscillations in the hippocampus.
Buzsáki, G. Theta oscillations in the hippocampus.
