Sentence examples for orthogonal methodology from inspiring English sources

We have attempted to remedy this by standardizing analysis pipelines, employing contemporary methods for removal of unwanted variation, and confirming our findings in multiple datasets generated by orthogonal methodology; however, we cannot entirely disprove the possibility of batch effects.

In this study, a complex medium for MPA production by P. brevicompactum ATCC 16024 was optimized by the orthogonal methodology employing a four factorial design at four levels in shake flasks.

For several of these targets, we further confirmed the SNP array results using a variety of orthogonal methodologies, including immunohistochemistry, FISH and qPCR.

With the use of four orthogonal methodologies, our results demonstrate that one cause for the variability in the frequency of reported methylation events is likely due to the method of assessment of methylation events.

During the development of PF-05280014, the proposed biosimilar was subjected to extensive side-by-side physicochemical and functional characterization using state of the art robust and orthogonal methodologies with reference product Herceptin sourced from the US and the EU (Ng et al. manuscript in preparation).

Thus, in an independent, external heterogeneous HNSCC cohort assessed by an orthogonal quantitative methodology, we confirmed the infrequent methylation events for the loci examined.

Independent external validation of these findings was provided by the TCGA cohort of HNSCC samples that were assessed by an orthogonal quantitative methodology.

Additional physicochemical and functional side-by-side characterization of PF-5280014 with trastuzumab-US and trastuzumab-EU using state of the art robust and orthogonal analytical methodologies will be published in a separate paper (Ng et al. manuscript in preparation).

The current paper outlines a proper orthogonal decomposition (POD) methodology for a flow field in a domain with moving boundaries.

The Taguchi orthogonal array design methodology was used to improve the 4-chlorophenol biodegradation ability of strain PHB5.

In our investigations towards regioselective and orthogonal cross-coupling methodologies on pyridine systems, 17 an interesting and unexpected byproduct was observed, which clearly originated from a direct arylation after C H activation (Scheme 1).