A specific working group organized in the Committee, focusing on spherical adsorbent carbon found significantly lower adsorption of iodine and methylene blue to the generic products compared to the originator formulation (Table 6).
Cell lines were purchased from ATCC or requested from the originator laboratories (Table S1).
Generally the procured price reductions were greater for generic formulations of the various PPIs than for the originator formulations (Table 2).
A prerequisite for all further downstream actions that combine to cause B cell depletion in vivo, the binding of GP2013 to its target CD20 was assessed in a cell-based competitive binding assay and was found to be well within the originator range (Table 2).
Generic oral rabeprazole in 2013 was 77% below 2004 originator oral rabeprazole (Table 2).
The analysis concerns all the biosimilar drugs marketed in Italy and their respective originator biological products (Table 1).
In such cases, the RD originator will update its routing table with the most recent routing information, it uses the route with the greatest destination sequence number.
Before applying the model, the baseline demographic characteristics for the placebo arms of the tibolone (originator) and EPIC studies were compared (Table 1).
The cost of ESAs treatment classified per Hb level, responders and non responders on originators and biosimilar, is presented in Table 4.
GP2013 was seen to be comparable to originator rituximab in CDC and ADCC assays (Table 2).
