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Lipid based delivery systems, originating from earlier research in the fields of gene delivery, are the most studied candidates for siRNA delivery.
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Originating from early Roman plantings and produced all through the Middle Ages, the wines have been blessed by religious orders, drunk by nobility and written about by scholars such as native son François Rabelais.
Brief psychodynamic therapy focuses on the identification of conflicts and unconscious processes, often originating from early developmental stages.
This is supported by the observation that late-born juveniles spend more time per day foraging above-ground during the prehibernation period (September/October) compared to those originating from early litters during the same time of year [48,49].
Many deep gas reservoirs in China's petroliferous basins also originated from earlier oil or oil gas reservoirs that were cracked into gas under high temperatures, as exemplified by the large Puguang carbonate gas field (Du et al. 2009), the large Kela-2 gas field (Jia et al. 2002), and the Hetian gas field (Wang et al. 2000).
Our interest in NRP-1 originated from earlier studies demonstrating its function as a co-receptor for VEGFR-2, facilitating VEGFR-2 binding of VEGF165 in endothelial and enhancing cell migration (Soker et al, 1998).
The POLIS systems originated from early work in 1988 and evolved into the Metropolis system under development.
The probe technique originated from early attempts of Anton van Leeuwenhoek to contrast microorganisms under the microscope using plant juices, successful staining of tubercle bacilli with synthetic dyes by Paul Ehrlich and discovery of a stain for differentiation of gram-positive and gram-negative bacteria by Hans Christian Gram.
Another variant proposes that eukaryotes originated from early archaea infected by poxviruses, on the basis of observed similarity between the DNA polymerases in modern poxviruses and eukaryotes.
Members of Filipino gangs, like Satanas, referred to themselves as "Pinoy Cholos" and took in the 'cholo' fashion -- some believing the oversized-clothes look originated from early Filipino farm workers.
5. Lughnasadh's alternate name, Lammas, derives from the Old English term for "loaf mass". It originated from early English celebrations of harvest time, during which loaves of bread were consecrated.
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