Recent investigations have been suggesting autophagy as a cell death pathway that may mediate cancer cells sensitivity to IR even though it could originate a protective mechanism against the treatment itself by removing proteins and organelles that are damaged or, alternatively, produce an effective cell death process [ 102].
The bone microstructure suggests that rauisuchian osteoderms were originated through a mechanism that involves both intramembranous and metaplastic ossifications.
In consequence, the expectation that pure regional types or races had once existed, and the quasi-infinite number of variants that the combinations of these types could have originated, was a mechanism solid enough to explain the observed variation.
Thus, the most plausible scenario is that a significant number of such hotspots originated through a mechanism other than spontaneous point mutations.
For this reason we removed the editing effect from the sequences, and sampled across a broad range of taxa....therefore, RNA editing originated as a mechanism to complement the low mutation rates in the organellar genomes.
We propose that bz1-m4-D6856 originated via a mechanism very similar to that shown in Figure 1: RET of two Ds elements located distal to the bz1 gene, followed by insertion of the excised Ds termini into an unreplicated target site in the bz1 5′ UTR region.
The zebrafish hybrid grn described here likely originates through a mechanism other than alternative splicing from a larger primary transcript since the grn2 gene is located 5' to the grn1 gene.
As indicated in Figure 5, the high correlation of Val75 with Asp30 and Asn88 (Fig. 5A), consistent with their structural proximity (Fig. 5B), may originate from a cooperative mechanism for drug resistance between these three sites.
Pseudoallergic angioedema and idiopathic angioedema originate from mechanisms that involve neither histamine nor bradykinin.
Our results further demonstrate that the changes of functional catecholaminergic effects on cytokine production in RA originate from various mechanisms instead of from a single cause.
