Sentence examples for originally appreciated from inspiring English sources
These results suggest that trans regulation of gene expression may be more common than originally appreciated and that where trans regulation occurs it can change dynamically during development.
This raises the possibility that other aspects of the sub phenotype may also have a more complex basis than originally appreciated.
Thus, the genomic co-localization of the two proteins may be even more widespread than originally appreciated, strengthening their functional relationship.
High mobility group box-1 (HMGB1) protein, originally appreciated as an intranuclear DNA binding protein, has been implicated as an integral mediator in the pathogenesis of animal arthritides and RA disease in humans.
Therefore, although there is clearly a strong association with those HLA-A allomorphs tested, TAPBPR interacts with a broader range of HLA molecules than originally appreciated (Boyle et al., 2013).
While originally appreciated for their anticancer properties, a growing body of evidence now supports the safety and efficacy of HDAC inhibitors in experimental models of liver and kidney disease, potentially expanding their clinical application.
Mr. Palmer, who is originally from the Caribbean, said he appreciated the area's increasing diversity, and also timeless pleasures like driving to a park on Gravesend Bay, going for a walk and enjoying the sea breeze.
"Originally, I don't think we appreciated how much the freemium model acted as a flywheel internally within an organization," said Quinn.
Originally priced at $660,000, the car has appreciated in value, according to Ali Karimi, a personal property appraiser in the assessor's office.
Michael Marion, a business analyst at Macy's, said that he appreciated all the talk about Michigan — he's originally from Clarkston.
While originally viewed as toxic mediators, these compounds have recently been appreciated for their anti-inflammatory role and oxidative stress suppression through the expression of phase II genes.
