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This phenomenon may produce an enlarged version of the original clusters.
Although the original clusters provide some structure to the input, this approach still demands for a high validation effort, especially when these clusters are not aligned with class labels.
The contamination of an anonymized cluster may depend on two factors: (i) there are elements corresponding to other original clusters or (ii) there are elements that were formerly noise and have been promoted to members of an anonymized cluster.
The reaction of etching leads to a remarkable depression of the UV vis absorption, which suggests that a transformation of the original clusters into extremely small clusters has occurred[21].
It is also observed that original clusters are fragmented into other clusters to some extent.
Searches were conducted with the same settings as for searches on the original clusters.
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The mapping of the forward and reverse reads indicates the sample of origin of the original cluster and was used to measure demultiplexing misassignments rates.
The 13 genes in the original cluster also themselves originated by repeated duplication, starting from a single Hox gene as found in the sponges.
Two metrics were considered to compare the resulting 38 LOO patient clusterings to the original clustering: coclustering probability and reduction in percent variance explained.
The four clusters of Hox genes found in mammals originated by duplication of the whole original cluster and retain considerable similarity between clusters.
But many of the genes in the original cluster remained, working together on the new tasks.
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