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We conducted a meta-review of studies that used the original AGREE instrument or AGREE II (henceforth referred to collectively as AGREE) to evaluate the quality of guidelines.
Country (UK) and type of developer (disease-specific foundation, non-profit healthcare system) appeared to be associated with applicability when assessed with AGREE II (not original AGREE).
Country (UK) and type of developer (disease-specific foundation, non-profit healthcare system) appeared to be associated with applicability when assessed using AGREE II (not original AGREE) though these findings should be interpreted with caution.
18 37 Guidelines were appraised with the original AGREE instrument in 9 studies and AGREE II in 11 studies.
The Appraisal of Guidelines for Research and Evaluation (AGREE) II is the second version of the original AGREE instrument to assess the quality of guidelines in terms of development process.
10 The latest version is AGREE II, which is a refinement of the original AGREE instrument.
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