The origin of shock was septic in 375 (69.2%) cases, cardiogenic in 24 (4.4%) cases, hypovolemic in 114 (21%) cases, vasoplegic without sepsis in 21 (3.9%) cases and unknown in 8 (1.5%) cases.
One important point is that there might be different behaviors among our patients, depending on the origin of shock, the degree of vasodilation, the supposed degree of capillary leak, and the shock severity.
Baseline characteristics of the study patients, including age, gender, Simplified Acute Physiology Score II, origin of septic shock and time from onset of septic shock until study drug infusion were similar among groups (Table 1).
The diagrams in Figure 8 show a well-known construction attributed to the Austrian physicist Ernst Mach that explains the origin of the shock front accompanying a supersonic projectile.
The origin of the shock, its expected duration, and its depth are all relevant to the optimal choice between these options.
Baseline characteristics including age, gender, body weight, origin of septic shock, and simplified acute physiology score II (SAPS II) are presented in Table 1.
Baseline characteristics including age, gender, body weight, origin of septic shock, and Simplified Acute Physiology Score II are presented in Table 1.
Approximately two-thirds of patients presented community-acquired infection, and more than half had respiratory tract infection (53.6%) as the primary site of infection at the origin of septic shock.
The factors found to be significantly associated with a shorter time to death, right censored at day 28, are shown in Table 5. Patients with urinary tract infection as the origin of septic shock had a significantly longer time to death (Table 5).
In addition, we further considered a subgroup of patients within the category of 'cardiac origin' of shock, namely those with cardiogenic shock, defined as having suffered a cardiac event associated with the combination of both cardiac index below 2.2 l/min per m2 and PCWP above 18 mmHg.
It is one of the proxies used by Beck et al. (2009) to capture the economic structure, which can be the origin of asymmetric shocks and differences in the transmission of such shocks.
