All 10 PEDV strains from South Korea were classified into subgroup 2b and most closely clustered together with the recent US strains in an adjacent clade with the same subgroup, suggesting that the US strains may be the origin of the recurrence of PEDV infections in South Korea.
As the absolute volumes of FDG PET-based tumour sometimes partly located outside the GTVCT domain were small, it was not possible to determine whether the exact origin of a recurrence lay located outside the GTVCT domain, but within the FDG PET-based tumour volume.
Thus, 5-ALA (Gliolan® -derived tumor fluorescence appeared useful for detectinGliolan® -derivedresidual infiltumoron in the dura but more importantly, also in the adjacent brain, which could be the origin ofluorescencecurrences; this happearedreviousefuleen reported.
Eradicating cancer stem cells, the root of tumor origin and recurrence, has emerged as one promising approach to improve lung cancer survival.
Indeed, stem cells are currently the subject of a large research effort in the biologist community; especially in case of cancers, where cancerous stem cells are suspected to be the origin of most of tumor recurrences.
Comprehensive analysis of SMCs by aCGH and FISH can distinguish unique-negative from unique-positive cases, determine the precise gene content, and provide information on mechanism of origin, inheritance, and recurrence risk.
It was proposed that a small population of tumor cells, named cancer stem cells (CSCs) due to normal stem-cell-like features, is responsible for origin, growth, recurrence, and drug resistance of several blood and solid tumors, including GBM.
Axial CT image shows the presence of hypodense soft tissue (white arrow) consistent with tumour recurrence, encasing the origin of the caeliac trunk and portal vein Open image in new window Fig. 29 Nodal tumour recurrence.
The authors concluded that the high risk of recurrence suggests the effects of recurring specific causal factors of genetic or environmental origin; however, they did not investigate the factors associated with recurrence.
Two patients died with no evidence of recurrence: one from pneumonia at 4 months and one from septic shock of digestive origin.
