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The origin of pain signals can be unclear to the sufferer.
Although the causes of low back pain are poorly defined and indistinct, degeneration of the intervertebral disc is most often implicated as the origin of pain.
Participants had moderate age-related beliefs about the origin of pain, but those who believed pain had an organic cause were more likely to seek help.
Nerve blocks may be utilized to relieve pain and elucidate the origin of pain; yet, they are only temporary measures.
We discuss the evidence against vasodilatation as migraine pain generator and some findings which we suggest in support of a central (brain) origin of pain.
There are many common features between the two pathologies: the symptomatology often overlaps and the origin of pain is regarded as "central"; indeed, the same neurotransmitters (serotonin, glutamate, P substance, CGRP) and receptors are involved [5, 6].
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These include thin unmyelinated C-fibers and myelinated Aδ-fibers, whose central terminals make synaptic contact with second order neurons that are at the origin of pain-related pathways [25].
Issues of chronic pain, disability, fetal pain, confinement, and torture present pressing questions about the underlying neurobiological origins of pain.
Different disease patterns may have pathophysiological implications, such as different origins of pain or mechanisms of chronification.
The peripheral and central origins of pain in cluster headache (CH) have been a matter of much debate.
The first 20 reported cases of EF [2, 3] had posterior origins of pain with forwards trajectories up to the ipsilateral eye or nostril.
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