Exact(4)
This difference could provide some useful insights into the the origin of overlapping genes.
Our results also imply that origin of overlapping genes is not an issue of saving space and contracting genomes size.
On the contrary, few studies discussed the origin of overlapping non-coding RNAs due to lacking of clear markers, like ORF in protein.
The mutational origin of overlapping genes typically involves point mutations to stop codons.
Similar(4)
Also, decadal and shorter signals originating in the Earth's core have been recently studied (Gillet et al. 2010; Silva et al. 2012; Holme and de Viron 2013; Cox et al. 2016); however, additional effort is needed to decide on the origin and degree of overlapping.
We consider three periods of the evolutionary process starting with the origin of overlap and the subsequent direct and indirect selection pressures acting on overlap length and phase.
In summary, we believe that our development of a simple method for estimating the selective strengths on overlapping genes will facilitate researches toward understanding the origin, evolution, and functionality of overlapping genes.
The embryological development of the genital tract and the urinary system is often described together, because of not only the proximity of the developing structures but also the large degree of overlapping origins.
Related(1)
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