Regardless of the origin, mechanism of emergence or precise genetic makeup of the 'next' pandemic strain, our recent experience with pH1N1 demonstrate clearly that the current, egg-based manufacturing system would not be able to respond quickly enough in the face of a highly pathogenic influenza virus adapted for rapid human-to-human spread.
This map also elucidates the role of these two features in the emergence of the birhythmic phenomenon: (1) is associated with a non smooth point of the return map whereas (2) leads to a discontinuity in the return map, which is at the origin of the emergence of the birhythmic behavior.
While our data show that exon shuffling most probably did not lie at the origin of the emergence of the PPN GHF5 endoglucanase domain structure, more recent exon/domain shuffling events at lower taxonomic levels cannot be ruled out.
Could it be that an episode of increased mutation and rearrangement rates is at the origin of the emergence of male-sterilizing factors in beet, being either new ORFs through intragenomic recombination as generally assumed (Chase 2007) or the outputs of deleterious mutations on essential mt genes positively selected as they disrupt pollen production (Budar et al. 2003)?
One of the biggest and most important of emergent phenomena is that of the origin or emergence of life.
The origin and date of emergence of this ST are unknown because of lack of microbiologic surveillance outside Niamey before 2002.
Resolution of the origin and frequency of emergence of ORVs and association with drug use clearly require substantially more intimate knowledge of the genetic relationships among OSVs and ORVs worldwide.
However, complete sequencing was necessary for an investigation of the origin and emergence of this virus in Europe, specifically in the Netherlands.
Reviewer 1: Eugene V. Koonin, National Center for Biotechnology Information, NIH, USA This manuscript addresses what I believe to be the ultimate problem in the study of the origin of cells: the emergence of the translation system.
This could suggest a naturalistic origin of original forms by material emergence or by means of a vitalistic power of life.
