Sentence examples for origin of disruption from inspiring English sources

Looking at the origin of disruption theory and the companies Christensen continues to get wrong, there's a clear pattern.

In order to understand the origin of this disruption of genomic links we decided to analyze the history of echinoderm ParaHox clusters and the roles of its genes.

Whereas the origin of the autophagy disruption is still unknown, mutations or loss of heterozygosity-dependent autophagy gene silencing (LC3, ATGs, UVRAG, BECN- 1) have been reported in many different cancers, such as colorectal, gastric carcinoma or breast cancers [ 32– 32].

Vacuolation was diffusely present in lesion areas lacking AQP4 and GFAP (Fig.  4d); it was observed only at the peri-vascular areas in early lesions (Fig.  4b) with disintegrated GFAP-positive foot processes, suggesting that the lesions of this model are of vasculocentric origin, with BBB disruption, followed by secondary extension of neutrophil infiltration and tissue vacuolation.

To test if disruption of an origin of replication can increase the local mutation rate in an early-replicating/low mutation rate region, the earliest and most efficient origin, ARS607, was deleted in strain GL·36, where the URA3 gene is located 3 kb away from the origin.

The aim of this study was to investigate the expression of a panel of LSGs covering all cortical layers (Cux2, Rorβ, Er81, Nurr1 and CTGF) in surgical specimens from a cohort of 20 patients with a neuropathological diagnosis of Type IIa/b FCD in order to learn more about cortical layering disruption and the origin of DNs and BCs.

It may be, for example, that the spirit of disruption, as outlined in Mr. Christensen's model, was latent in the very origins of the United States, helping to account for its persistent recurrence here.

Closer examination of the trajectories revealed the origin of the stochasticity: dimer opening requires simultaneous disruption of several H-bonds between the nucleotide and the opposite NBD.

Thus, both poorer semen quality and shorter AGD in adulthood may reflect a common origin, including a disruption of testicular development in utero, as suggested by the testicular dysgenesis syndrome (TDS) hypothesis (Skakkebaek et al. 2001).

In human males, shorter AGD in adulthood has been associated with poorer semen quality [ 21, 22] and infertility [ 21] suggesting a common origin, including a disruption of testicular development in utero, as suggested by the testicular dysgenesis syndrome hypothesis [ 42, 43].

This process of disruption is nothing new.