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Even so, little is known about the origin of deficit accumulation.
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Although, recent findings have identified a genetic origin of GSH deficit, which results in the impairment of the GSH synthesis in patients diagnosed with schizophrenia [ 51].
A causal origin of this deficit may be a specific processing impairment for certain kinds of lexical elements especially grammatical function words and inflectional affixes (Caplan, 1982 , 1987 Goodglass, 1997; Kolk, van Grunsven, & Keyser, 1985; Pulvermüller, 1995).
This encourages the extension of past and future thinking research to TBI populations to provide important insights into the nature and origin of these deficits and their role in recovery and to suggest future lines of research on rehabilitation procedures.
The physiological origins of the deficit have been extensively investigated using single-cell neurophysiology in animal models with amblyopia produced artificially using a surgically induced strabismus, optically induced ansiometropia, or from deprivation by monocular lid suture.
To understand the origin of this processing deficit we must consider the anatomy of the intact model, in which the context stream has a denser projection than the object stream, with lower average weights (see 'Model architecture' for rationale).
Device-based CRT corrects conduction delays, yet fails to address parenchymal loss that is at the origin of the contractile deficit post-infarction.
However, the definitive origin of these neuromuscular deficits remains to be investigated.
The specificity and the neurobiological origin of these connectivity deficits and the relation to the symptom complex of schizophrenia and the glutamatergic and GABAergic system are discussed.
If nevertheless differential effects can be found for neglect patients when performing such a task, this would also be informative with respect to the current debate on the origin of neglect-related deficits in number processing.
To further address the origin of the motor deficits in mice ICV-injected with 100 µg ASO-20-37 ASO-20-37 ASO-20-37naptic connectivity betweexaminedry afferentheand motor neuronsynaptici-vesiconnectivityate transporter 1 (VGLUT 1) immunostaining for glutamatergic excitatory synapses (Oliveira et al, 2003).
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