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In contrast to spontaneous origin of activity, active states in neurons driven by already activated network should exhibit faster depolarization at the transition from the silent to active state.
By utilizing the scheme, we demonstrate that the origin of activity variance lies in the geometric structures.
In this paper we have investigated the spatial origin of activity during each cycle of episodic activity.
Unfortunately, in the previous work, it was not possible to investigate the origin of activity in each cycle because calcium signals are relatively slow compared to electrical activity and because video-rate imaging integrates the optical signals within a single frame.
For this reason, in the present work we used high speed multi-site optical recording from an en bloc slice preparation of the chick embryo spinal cord (E8 to E11) labeled with a voltage sensitive dye to establish the spatial origin of activity at the onset of each cycle.
Three hypotheses on the origin of activity have been proposed.
Similar(52)
The structure-based in silico methods use structures of ligand-target complexes to identify the structural origins of activity and selectivity of related ligands.
In most ectotherms, the majority of Ca2+ necessary for contraction is extracellular in origin, regardless of activity level (1, 10, 16, 24, 37, 45, 49).
The precise evaluation of each surface site's activity is important to obtain a fundamental understanding of the origin of catalytic activity.
This reaction, Newton said, was the origin of volcanic activity.
Thus, the origin of inhibition activity of at least one S. mitis strain remains unclear.
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