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In principle the apparently late origin of a process can be attributed to lack of selective advantage, lack of suitable phylogenetic precursors, or its inherent mutational/mechanistic difficulty.
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Hindle and Lubar (1986) view invention as the creative origin of a new process that enables innovation.
Such a selective pressure on these proteins could be at the origin of a divergence process between species and thus contribute to the speciation phenomenon by reinforcing prezygotic barriers.
Finally, the data reported in the literature tend to support the concept that the mammary gland contains Stem cells 1 that could be the progenitor of the differentiated breast or could be the site of origin of a neoplastic process.
Angiogenesis involves the development of blood vessels of capillary origin, a process tightly controlled by proangiogenic factors such as fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor (VEGF).
After sequencing, reads must be assigned in silico to the sample of origin, a process referred to as demultiplexing.
Experimental data suggest, that CTCs can be released from metastatic tumors and then rejoin the tumor of origin, a process termed 'self seeding' [ 28, 29].
Further, CTC have also been known to colonize their tumors of origin, in a process called "tumor self-seeding".
Molecular dynamics (MD) simulations of cis-1,4-polybutadiene in bulk amorphous state were performed to elucidate the origin of a fast relaxation process observed by quasielastic neutron scattering (QENS) measurements.
It is thought that many apomictic species may be of hybrid origin, a process that can prevent normal meiosis [ 49, 50].
If we assume a geographic origin in Central Asia, a process of rapid recent expansion from this area towards the Mediterranean region, and probably Australia, would explain the phylogeographic pattern observed on its populations.
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