Exact(13)
PSC origin (lineage tracing studies).
Regardless of the origin (lineage) of those cells, one could think of them as SCs - based on the definition of such cells.
Based on their lineage origin, they can be divided into two major subsets, plasmacytoid DC as the major producers of type I interferon and myeloid DC [15].
In the opposite case, the mouse lineage origin is the most parsimonious hypothesis.
In the end, we obtained 41 breakpoint pairs of human lineage origin (17 reciprocal and 24 non-reciprocal), 121 of mouse lineage origin (27 reciprocal and 94 non-reciprocal) and 167 of unknown origin (9 reciprocal and 158 non-reciprocal).
The resulting dendrogram clearly grouped the samples first by patient replicates using three different extraction methods and secondly separates the leukemias by lineage origin in B lineage ALL (orange), T lineage ALL (blue) and AML (green).
Similar(47)
Positive selection was inferred for four genes, ASMTL, GTPBP6, IL3RA, and P2RY8, all on the primate-origin lineage (Table 3).
Maximum-likelihood analyses detected four genes (of 29 analyzed) in the 3 Mb typically deleted VCFS region as subject to positive selection in the primate-origin lineage (Table 3).
None of the seven genes analyzed spanning GTF2I to LIMK1 demonstrated statistical significance in maximum-likelihood analyses, although RFC2 showed borderline nonsignificance (0.05 < P < 0.06) for the primate-origin lineage (Table 3).
Using PAML, the RAI1 gene was inferred as subject to positive selection for the primate-origin lineage (Table 3), but not in the human or human chimp lineages, nor in the human HapMap data.
Our finding that positive selection was especially prominent along the primate-origin lineage suggests that molecular-evolutionary changes underlying important features of complex social cognition were established well before separation of the human lineage.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com