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No significant sex by ethnic origin interaction was observed for adiponectin.
Second, the temperature × pathogen origin interaction was statistically robust against variation between replicate experiments (Table S3).
1 Joint test of main effects of SNP, Origin, and the SNP × Origin interaction.
First, the temperature × pathogen origin interaction indicated differential performance of northern and southern isolates at different temperatures.
Because we did not find significant population × origin interaction in the multivariate GLM (see Results), we did not address habitat × origin effects with GLMMs.
As for phage evolution, bacterial evolution depended on phage isolate identity (bacteria type × phage isolate origin interaction: F3,28 = 4.5, P = 0.0328; Table S1).
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Moreover, a significant effect of the temperature × population-origin interaction was detected for biomass production, total length and branch production.
The marginal logistic regression model used to describe the data found a significant (p < 0.05) association of herd size cow-origin interaction.
No significant medium-by-origin interaction effect was detected for the growth rate and the carrying capacity.
Clustering of the origins in defined nuclear regions appears to play a role (Duan et al., 2010), as highlighted by a function for the forkhead transcription factors in promoting origin-origin interactions at early replicating regions of the budding yeast genome (Knott et al., 2012).
Three models were used for the association study: (1) conventional GWAS (genome-wide association study), fitting a single SNP effect regardless of subspecies origin, (2) interaction GWAS, fitting an interaction between SNP and subspecies-origin, and (3) best variable GWAS, fitting the most significant combination of SNP and sub-species origin.
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