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No clones were recovered, in contrast to a plasmid carrying a p15A origin, functional in Vibrionaceae.
For each cancer gene we retrieved duplicability, evolutionary origin, functional annotation, gene expression profile, protein protein interaction and gene-microRNA interaction.
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However, an ACS alone is not sufficient for origin function and this sequence is much more abundant than the number of ORC binding sites or functional replication origins [ 20, 22].
This approach to trace the evolutionary origin of functional domains in the human proteome facilitates better understanding of their functional versatility as well as provides insights into the functionality of hypothetical proteins present in the human proteome.
To gain understanding into the origin and functional consequences of sexual heterochrony, we studied the expression profiles and functional properties of the 654 genes showing accelerated female timing in SFG.
PACAP displays numerous functions in cells of neuronal and non neuronal origin and functional VIP/PACAP receptors have been demonstrated on PMNs, mediating Ca2+- dependent pro-inflammatory activities through the activation of multiple regulatory pathways [71].
For the families with resolved phylogenies we observed a clear dichotomy in terms of evolutionary origin and functional roles: all proteins with a specific bacterial origin have enzymatic functions while most proteins (90%) with eukaryotic origin are functioning in peroxisome organization and biogenesis.
Some present-day concepts on the origin and functional activities of dinitrosyl iron complexes (DNIC) with thiolate ligands are considered.
The structural organization of biological systems is one of nature's most fascinating aspects, but its origin and functional role is not yet fully understood.
While theoretical studies have contributed significantly to our understanding of how the brain learns to see, recent experimental discoveries of the spatial irregularity of visual response properties in the rodent visual cortex have prompted new questions about the origin and functional significance of cortical maps.
The evolutionary origin and functional consequences of these cerebral asymmetries remain to be explained.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com