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The OriDB (www.oridb.org) DNA Replication Origin Database was used as source and reference to collect the ACS expanded motifs, and localize ARS [29].
Data will also be available at the DNA Replication Origin Database [ 64], which includes a graphic viewer format of the nimARS data similar to that of Figure 7B.
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Trends in International Migrant Stock: Migrants by Destination and Origin (United Nations database, POP/DB/MIG/Stock/Rev.2015, available from http://www.un.org/en/development/desa/population/migration/data/estimates2/estimates15.shtml).shtml
This locus was not found in the Imprinted Gene and Parent-of-origin Effect Database (Morison et al. 2001).
Further, a review of the 'imprinted gene and parent-of-origin effect' database [available at http://igc.otago.ac.nz/home.html] [ 78] did not yield any evidence supporting imprinting at either locus.
We modeled variation in cDNA pool coverage according to database origin, enzyme combination and the interactions of database origin and GC content with the enzyme combination (see additional file 4) in addition to the main effects of the covariates listed above.
As these differences could introduce an additional source of variation in our analyses, we investigated the importance of database origin, using the 21 taxa for which data were available from both repositories (see additional file 3).
The species and database origin was contained in the sequence identifier.
Twenty-one species were present in both databases, providing an opportunity to investigate the potential effects of database origin on pool coverage.
The date of origin of each database ranged from 23 February 1990 for the oldest to 2000 (seventh centre) for the newest.
The identifiers of all the sequences used, and their respective database origin, are listed in the Additional file 2: Table S1.
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