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Enzyme activity (depends on enzyme origin and level of purification) and enzyme loading (amount of enzyme/g substrate; based on experimental conditions) information was transformed into theoretical maximum turnover number (maximum possible number of bonds hydrolyzed per unit time for each enzyme) (N hi_max) (Eq. 1) for each class of enzyme.
The number of subjects who could be assessed varied from family to family, but was apparently unrelated to the dimension of the kindred, site of origin and level of education.
Additionally, we were able to adjust for individual factors correlated with both exposure and risk such as BMI, maternal origin and level of education, which might otherwise have acted as confounders, at least in the case of SGA.
DisGeNET data have been aggregated according to origin and level of curation into CURATED (expert-curated associations obtained from UniProt and CTD human datasets), PREDICTED (containing human GDAs inferred from mouse and rat models, i.e. CTD mouse and CTD rat datasets, and RGD and MGD datasets), and ALL.
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In addition, 120 Alu Ye4, Ye5 and Ye6 loci were screened using polymerase chain reaction (PCR) assays to determine their phylogenetic origin and levels of human genomic diversity.
To minimize potential selection bias through peer researcher recruitment approach and to enhance representativeness of study population, we provided a weekly summary of recruited study population by sex, age, country of origin, language and level of education and encouraged peer researchers to approach certain under-reached groups.
We tested the hypothesis that systemic vascular activation contributes to CM by examining origins and levels of plasma MP in relation to clinical syndromes, disease severity and outcome.
Multivariable logistic regression was used to control for confounding by step-wise adjusting for age, sexual debut, and area of origin, and educational level of head of household.
Among these inhabitants, immigrant-related determinants other than country of origin, fluency in Dutch and level of education may have an effect on the level of compliance with occlusion therapy.
The PTTG1 protooncogene has been detected in several tumors of unrelated histological origin, and its level of expression has been associated with the aggressiveness of the primary neoplasia [ 8, 11].
In order to ensure the heterogeneity of the participants' profiles, three criteria were established: age (15 17 or 18 24), origin (cities, towns, or villages), and level of education (ranging from primary education to university studies).
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