Sentence examples for origin activation from inspiring English sources

Second, replication origin activity, including origin assembly and origin activation timing, can be positively regulated by histone acetylation in a variety of systems (8, 9).

This would also address the question, whether the frequency of origin activation is based on an active process or depends on non-linear origin usage.

Finally, origin-specific trans-acting regulators of origin activity could be cell-type specific, allowing an additional level of regulation of origin activation.

Our results suggest that the program for origin activation is largely conserved among different cell types.

The surrounding genetic and epigenetic elements could also separately affect the efficiency of origin activation.

The decrease of K36me3 raises the possibility that a histone demethylase is directly recruited and aids origin activation.

If this was the case, then one would not expect histone modifications to change during origin activation.

The time-dependent rate of replication origin activation, I t), is defined as an average over the whole genome.

The quantitative model previously proposed for origin activation in X. laevis can be generalized to explain this evolutionary conservation.

Binding to these factors, however, is likely to occur at a later stage during the origin activation process.

We provide evidence that recombination-like X structures form at OriP following replication pausing and origin activation.