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After sequencing, reads must be assigned in silico to the sample of origin, a process referred to as demultiplexing.
Experimental data suggest, that CTCs can be released from metastatic tumors and then rejoin the tumor of origin, a process termed 'self seeding' [ 28, 29].
It is thought that many apomictic species may be of hybrid origin, a process that can prevent normal meiosis [ 49, 50].
Angiogenesis involves the development of blood vessels of capillary origin, a process tightly controlled by proangiogenic factors such as fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor (VEGF).
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Further, CTC have also been known to colonize their tumors of origin, in a process called "tumor self-seeding".
In principle the apparently late origin of a process can be attributed to lack of selective advantage, lack of suitable phylogenetic precursors, or its inherent mutational/mechanistic difficulty.
During the G1 phase, pre-replicative complexes (pre-RCs), composed of the origin recognition complex (ORC), Cdc6, Cdt1, and an inactive form of the replicative helicase Mcm2-7 complex are assembled into ACS-containing origin regions, a process called 'licensing' [ 2].
A process involving the origin of biodiversity after life had originated 2. A process involving the origin of the universe 3. A process involving the origin of life 4. Uncertain.
If we assume a geographic origin in Central Asia, a process of rapid recent expansion from this area towards the Mediterranean region, and probably Australia, would explain the phylogeographic pattern observed on its populations.
For instance, a recent publication on the topic concluded that self-reported health is a unique indicator of human health status; its origins lie in a process whereby information from the individual's body and mind is received, selected, reviewed and summarized and therefore it could predict the most absolute biological events, such as survival or death [ 121].
DNA replication is initiated from multiple replication origins on a chromosome, in a process often termed origin firing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com