Our current implementation of TIP is limited in that it is oriented toward bacteria, and does not perform well on eukaryotic compartments.
The η-NH2 group of NOHA is oriented toward Mn2+A (but does not coordinate) and donates a hydrogen bond to E307.
The ζ-NH group of nor-NOHA donates a hydrogen bond to D158, and the ζ-NH2 group is oriented toward Mn2+B (but does not coordinate) and donates a hydrogen bond to T276.
We conclude by proposing a set of questions across these three dimensions that health policy and systems researchers may wish to consider in making their practice more people-centred, and hence more oriented toward real-world change: Does the research explicitly address dynamism and complexity, allowing for the social, political, and economic drivers of human behaviour?
Selected patients, comparators, time-frame, and outcomes, among other factors, are oriented toward regulatory approval and do not always reflect the routine clinical practice environment.
"People who are oriented toward quality and design do more of their shopping at Target," Mr. Ulrich said in a recent interview.
Recent work has highlighted a distinction between "resistance" type immune mechanisms, in which the host attempts to eradicate an invading organism, and "tolerance" type mechanisms, in which the host response is oriented toward reducing the damage done by infection (Schneider and Ayres, 2008).
"Everything we are doing is oriented toward our ability to leave," he said, adding that the most likely obstacle to leaving by April would be the continued failure of the Interior Ministry to supply the police.
Val115, which is oriented toward the substrate in hDHFR, does not appear to have the sensitivity to substrate that the larger Ile side chain in ecDHFR does.
The guide is not strictly about Internet stocks, but does seem oriented toward small investors seduced by online trading.
Peter Van Wyck, the president of the Charlotte Brontë's board, has one of the apartments oriented toward the street, although he does get partial views of the river from several rooms.
