Based on the orientation of alignment to the predicted protein structures, transcription of this element would occur in the 3′- to 5′-direction relative to the SDR scaffolds if it were functional.
The similar overall numbers of Plus 2.0 and DSA probesets unambiguously mapping to the HTR database were contrasted when the orientation of alignment was considered, with the Plus 2.0 showing slightly higher numbers of sense features and the DSA showing significantly higher numbers of antisense transcripts.
The insert lengths between paired ends were compared to the corresponding distances between their alignments against the reference genome in order to detect indels, and inversions were detected by disparate strand orientations of paired alignments.
The N−H bond vectors associated with these residues happen to lie at a critical angle relative to the alignment tensor, where even small variations in the orientation of the alignment tensor produce substantial changes in the corresponding RDC.
mugsyWGA first builds an alignment graph using the refinement approach described in SeqAn::T-Coffee (Rausch et al., 2008), with the addition that the orientation of the alignment between segments is also saved.
The goal of this study was to probe the effect of orientation and alignment of carbon nanotubes (CNTs) embedded in an epoxy polymer matrix under a magnetic field on the mechanical properties of the resulting nanocomposite.
SVs were called depending on (1) whether the two aligned regions were on the same chromosome, (2) the distance between the two aligned regions if they were on the same chromosome, and (3) the orientations of the two alignments.
Here, we demonstrate simultaneous control of alignment (orientation) and dispersion (location) of pristine, i.e., unfunctionalized MWCNTs using a high molar mass (HMM) amphiphilic block copolymer (BCP).
In principle, the attained resolution (the minimum size of the structural detail that can be resolved) depends on the number of images averaged, their homogeneity (they should represent the same protein in the same orientation), and the accuracy of alignment; however, in practice the problem is difficult and remains the subject of vigorous research.
This structure-based method was used here to calculate the orientations of lysozyme in two alignment media, one steric (DMPC/DHPC) and one electrostatic (DMPC/DHPC/CTAB).
