No derailment means there is no possibility that whenever a train is moving over a point enroute towards its destination, that point suddenly changes its orientation, causing the train to move in two directions at once resulting in derailment.
In an interview with ABC last Sunday, he said "my orientation's going to be to move forward" rather than looking back.
The walkout, the second at Yale this year and the ninth since 1968, has strained tempers at the start of the school year, shutting down most of Yale's dining halls, disrupting freshman orientation and causing some teachers to move classes off campus.
On the other hand, I also have a belief that we need to look forward as opposed to looking backwards... My orientation is going to be to move forward".
Bi-orientation, therefore, needs a mechanism to move chromosomes closer to the opposing SPB, which depends on Bub3 and Bub1 (Fig 4A; supplementary information online, note 7).
By forming a looping structure, PolII needs to have a preference for its movement as it needs to move towards the transcription orientation of the associated gene.
Sargeant's mind is not too far afield from this model: always ready to move or change orientation, but in a graceful, less shambling manner than Mailer.
In order to steer all robots to move with the desired orientation and speed, we then introduce a number of leaders into the system, and quantitatively establish the proportion of leaders needed to track either constant or time-varying signals.
It is one thing to move the ball, another to know its precise orientation once you've done so.
