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Keeping in mind that the driver face database is composed of face examples for five different orientations, the face is passed to the neural network to determine its orientation, specifically for the up and down cases.
Our results contribute to an emerging model of the peptidyl transfer reaction in which the ribosomal active site positions the substrates in an orientation specifically designed to promote the reaction, wherein the A76 2′-OH serves as a proton shuttle to enable critical proton transfers in the formation of the final peptide product.
It may be that valid cues to sexual orientation – specifically those that are more likely be gender atypical in reality – are more easily detected in highly sex-typed targets.
To validate the results of the circRNA sequencing analysis, we designed primers in divergent orientation, specifically capable of amplifying the junction region of the circRNA (Fig. 3A; primer pairs listed in the Materials and Methods section) for the circRNA transcripts identified in Fig. 2. A subset of circRNAs detected by RT-qPCR analysis is shown (Fig. 3B).
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Although we extensively focused on the co-directional orientation, we also examined the long overlaps in the other orientations, specifically, 75 divergent overlaps and 178 convergent overlaps longer than 60 bps.
Approximately three-quarters of all participants agreed that an orientation program specifically targeted for IMGs is needed.
The fact that mInsc induces production of IPs and basal RGs suggests that its effect on spindle orientation may specifically regulate indirect versus direct neurogenic asymmetric divisions [ 40 ].
If individuals were excluded from the parent study during phone or orientation screening specifically due to scheduling conflicts, they were called back later to assess their potential eligibility for participation in the MTSO study.
The key to this idea is the catalytic interaction between the two closely opposed GTP molecules in anti-parallel orientation and, specifically, the crystallographically determined, catalytically important reciprocal trans interactions between the 3'OHs and the γ-phosphates [ 20, 21].
Five BP100 derivative peptides, including up to three copies of BP100 in the same or in opposite orientations, were specifically designed for expression in plants and accumulation in the ER.
An association exists between such positioning and clinical outcomes (specifically, orientation toward the interventricular septum has negative prognostic implications).
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