Sentence examples for orientation of variable from inspiring English sources

Three of the selected structures were used as templates for Vl (identity 68 92%), five of them as templates for Vh (identity 66 86%) and one structure was used as a template for proper orientation of variable domains in Fv.

This suggests that the orientation of variable fragments in the construct did not influence dramatically the folding and subsequently the antigen-binding capacity of the scFv.

The length of the linker between HC- and LC-variable fragments and the orientation of the variable fragments, both of which may influence expression, stability and functionality, that is, binding capacity [ 36, 37], were examined with 48scFv produced in E. coli.

The elbow angle, which is commonly used to describe the relative orientation of the variable versus the constant domains of each Fab fragment, differed significantly between the two 7C8 molecules present in the asymmetric unit with 138° and 184° for 7C8 monomer 1 (chains A and B) and monomer 2 (chains H and L), respectively (Figure 1C).

Due to their high reactivity the opened bridges can anchor a gold plate more efficiently than other sites of the macromolecule giving rise to preferential orientations of the variable part of the antibody.

Our work has demonstrated the effectiveness of ultrashort UV laser pulse in breaking the disulfide bridge in antibody thereby producing highly reactive free sulphurs that allow the right orientation of the antibody variable part (the so-called Fab region).

In Experiment 2, observers detected symmetry in tests of variable orientation in the presence of either non-symmetric or symmetric masks filtered for orientations either parallel or perpendicular to the axis.

The influence of matrix anisotropy of variable orientation on single layer folding is investigated using finite element models.

The first is characterised by the widespread reactivation of Mesoproterozoic structures, resulting in a network of shear zones of variable orientation, and the second is characterised by the development of crustal-scale transpressional shear zones, motion on which has caused the rotation of lithospheric blocks and the reorientation of prior structural trends by up to 90°.

The remaining 5 clones had the reverse orientation and 5′ UTRs of variable lengths.

We investigated human sensitivity to vertical mirror symmetry in noise patterns filtered for narrow bands of variable orientations.