Sentence examples for orientation machinery from inspiring English sources

Moreover, recent data in cellular models and in vivo have shed light into the underlying mechanisms that connect the spindle orientation machinery with cell polarity.

The last few years have witnessed tremendous growth in understanding both the extrinsic and intrinsic cues that position the mitotic spindle, the varied mechanisms in which the spindle orientation machinery is controlled in diverse organisms and organ systems, and the manner in which the division axis influences the signaling pathways that direct cell fate choices.

Spindle orientation machinery.

Upon RNAi silencing of the tumor suppressor adenomatous polyosis coli (APC), which is known to regulate spindle orientation (Yamashita et al., 2003), ISC divisions become parallel to the basement membrane, indicating that the spindle orientation machinery is involved.

ABL1 localization and DNA binding were regulated during the cell cycle by the retinoblastoma protein and it was recently discovered that ABL1 might be a key component of the spindle orientation machinery [ 24, 37].

To understand the context in which GKPIDs evolved, we also sought insight into the evolution of other components of the spindle orientation machinery – and spindle orientation itself – by examining their presence in the single-celled eukaryotes most closely related to animals.

Thus, planar spindle orientation may be an active process of orienting the spindle, while oblique and vertical orientations may reflect a more passive result of inhibiting this orienting machinery.

If we're all equal, then we shouldn't be judged by skin color or sexual orientation, and the machinery of democracy shouldn't be gummed up by outdated racial classifications.

Finally there could also be a link between hyperphosphorylation of Tyr1 in AS orientation and exosome machinery recruitment to degrade nascent RNA prior release of the Pol II enzyme (Preker et al., 2008; Andersen et al., 2013).

This annealing event promotes the desired genome dimer orientation and exploits host replication machinery and DNA repair enzymes for intermolecular recombination with the resultant junction sequence corresponding to the sequence of the oligo.

In other words, it is far from obvious that monkeys, in spite of their powerful cortical machinery to process orientation, consistently and preferentially rely on edges and corners, rather than on unoriented feature elements, when engaged in pattern vision.