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10.7554/eLife.10147.012 Figure 3. Taxonomic distribution of proteins in the spindle orientation complex.
Our analyses do not establish a complete history of the spindle orientation complex.
10.7554/eLife.10147.021 Figure 8. Historical evolution of GKPID-mediated spindle orientation complex.
The left portion shows major events in the evolution of the components of the spindle orientation complex reconstructed in this study.
Recently, a spindle orientation complex has been identified at the mother spindle pole containing protein components that promote maturation (Yamashita et al., 2007; Izumi and Kaneko, 2012; Chen et al., 2014).
For example, it is not known when the GKPID's scaffolding functions first evolved, either in relation to the emergence of organized multicellularity or the origin of the other components of the spindle orientation complex; it is therefore unclear how the complex was assembled by evolution or what its role may have been in the emergence of spindle orientation and tissue organization.
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However, in other grain orientations complex structures appeared in all materials and dense dislocation networks formed at higher doses.
A key tool of policy debates and policy learning alike are policy narratives to provide a simplified orientation of complex value-laden policy issues (Shanahan et al., 2011; Urhammer and Røpke, 2013).
When a new target signal is significantly off-axis, directional microphones lead to slower target orientation, more complex movements, and more reversals.
Surface modification has shown to be a convenient route to promote the orientation of complex structures, like cytochromes, or contain electroactive flexible polymers to produce efficient electron transfer processes, transforming the flat electrode surface in a three-dimensional structure.
The methodology permits identification of the local thermo-mechanical stress strain response at critical locations and prediction of fatigue life and cracking orientation for complex transient, anisothermal, cyclic elastic plastic-creep matelastic plastic-creep
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