The point of divergence in the NADPH orientation is centered on residue Gly18, which, in bacterial DHFR enzymes, is typically a larger and polar Asn residue.
A grid box, large enough to avoid biases of the docking results to a certain ligand orientation, was centered on the previously described heparin-binding site (H23, K25, R65, K69, K72 and R73; Kuschert et al. 1998).
In a given trial, a reference line for a fixed orientation was first presented for 300 ms, followed by a blank screen for 600 ms, and then a test line with 1 of 7 orientations (equally spaced intervals, centered on the reference orientation) was presented for another 300 ms at the same location.
Despite its widespread popularity, the series has been involved in several public controversies, including one centered on speculation over SpongeBob's intended sexual orientation.
The second college media controversy of the summer centered on an orientation issue has surfaced at North Carolina State University.
An orientation histogram with 36 bins covering the range of 360 degrees is used to accumulate the local gradient orientations within a square region centered on a feature point.
Nine data points (covering 180°; steps of 22.5°) centered on the preferred orientation were selected and used for the rest of the experiment.
Hydroxyl orientations were binned as gauche, anti(t) or gauche centered on −60, 180 and 60°, respectively.
The acquisition volume was positioned in an oblique axial orientation, tilted forward parallel to the Sylvian fissure, and approximately centered on the superior temporal sulci.
To Ms. Willis, the museum is a starting point, an orientation center for the city's collection of skyscrapers.
