The islet is a highly organized functional micro-organ with defined size and structure, intercellular coupling, and autocrine and paracrine regulations.
The notion that there is an organized functional relationship between DNA methylation and tissue-specific biological function is supported by the data presented in Figure 6A in which we identified a clear correlation between tissue specific methylation and cell type specific biological function in MBCs.
It has been shown recently, that eukaryotic genomes are highly organized functional architectures with a large number of long-range DNA cis-interactions29,30,31,32,33,34.
For natural selection is the only theory that can explain the existence of organized functional complexity in nature (Pinker 1994 , 1997.
Living entities metabolize, grow, die, reproduce, respond, move, have complex organized functional structures, heritable variability, and have lineages which can evolve over generational time, producing new and emergent functional structures that provide increased adaptive fitness in changing environments.
Suppose, as suggested above, that an organism's teleological profile is indeed shaped by the facts of the evolutionary history that ultimately explain how it was put together as the organized functional system it is.
Although little is known about a number of these domains, they are significant in that they show that the nucleoplasm is not uniform mixture, but rather contains organized functional subdomains.
We organized functional gene subsets based on gene annotation and pathway information.
The reactions in the database are classified into hierarchically organized functional group categories.
However, limited focused and organized functional genomic datasets exist on drought-responsive plant USP genes to facilitate their characterization.
